Alli and Xenical Kidney Damage Side Effects

Harvey Kirk

By Harvey Kirk
Posted April 18, 2011


According to new research, there may be a risk of kidney problems from side effects of Xenical and Alli, two weight loss drugs that contain the active ingredient orlistat. The medications have previously been linked to a possible risk of serious liver side effects, raising serious concerns about whether the minimal weight-loss benefits justify the potential risk of potentially life-threatening organ damage.

>>PRIOR POST: Xenical and Alli Liver Damage Side Effects

The product liability lawyers at Saiontz & Kirk, P.A. are evaluating the potential for Xenical and Alli lawsuits for individuals who have experienced kidney problems or liver damage after using either of these weight-loss products.

About 1 in 50 users of Xenical (orlistat 120mg) could expect to be hospitalized for kidney problems, according to Canadian researchers. This may also cause concern for users of Alli (orlistat 60mg), which is a lower dose version of Xenical that is sold over-the-counter.

The study, which was published recently in the Archives of Internal Medicine, examined data on 953 users of Xenical in Canada and found that 2% were hospitalized for kidney damage over the last year, compared with only 0.5% for the rest of the population.

The researchers have cautioned that their findings don’t indicate a cause-and-effect link between Alli or Xenical and kidney damage, but they noted that there have been single-person case reports that suggested that the weight-loss drugs could cause oxalate-induced acute kidney injury.

These potential concerns about the risk of Alli or Xenical kidney problems come more than a year after the FDA indicated that it was beginning to investigate a potential risk of liver problems from Alli and Xenical side effects. In August 2009, the federal drug regulatory agency indicated that at least 13 reports of severe liver injury from Xenical had been received among users, including two of which resulted in death.

Last week, the consumer watchdog group Public Citizen filed a petition with the FDA to issue an Alli and Xenical recall, saying the drugs appear to have potentially lethal side effects that negate any minimal weight loss health benefits.


While information is still being investigated regarding these potential Alli and Xenical problems, the lawyers at Saiontz & Kirk, P.A. are reviewing potential injury lawsuits for users of the medications. Free consultations and claim evaluations are being provided to help individuals determine whether they may be entitled to compensation through an Alli Lawsuit or Xenical lawsuit.


10 Comments • Add Your Comments

  • constantine says:

    i am awating a kidney transplant on march 12th . took alli for a year

    Posted on February 26, 2012 at 3:26 pm

  • Danielle says:

    I just recently had my kidney removed. Took Xenical for years.

    Posted on September 2, 2012 at 12:10 am

  • Amy says:

    I have been using xenical for way too long which I thought was helping some of my digestive problems along with keeping my weight in check. I have recently got blood results with High BUN levels.

    Posted on September 26, 2012 at 5:10 pm

  • Mark says:

    Took Alli I for about three years stopping a few months ago. I now have an appt with the renal clinic in June due to blood test results and ultrasound.

    Posted on May 20, 2013 at 11:18 pm

  • Rodney says:

    I took All I for about a year. I have now been on kidney dialysis for 4.5 years.

    Posted on August 24, 2015 at 2:19 pm

  • Anna says:

    I have taken Alli since it came back on the market over a year ago. My blood tests came back having high Creatine and Bun numbers for the first time. I had an ultra sound and it showed a cyst on my kidneys. Now going for a scan of liver and renal doctor.

    Posted on June 29, 2016 at 7:41 am

  • Leila says:

    I have kidney disease stage 4 to 5 now doctors said I need dialysis and transplant, I feel very sad to took this evil Xenical under the counter I really don’t know this will mess up my life now I am scares to die and leave my 10 and 11 years old children’s is very sad and I hope nobody believe in pills to loose weight you can loose your life. I just want my normal life back is all what I want.

    Posted on February 6, 2021 at 12:12 pm

  • Brenda says:

    I took Alli for years to control my weight Now I have stage 3 kidney disease, Wish I had known then that taking Alli would effect my kidneys

    Posted on May 18, 2021 at 4:07 pm

  • Randi says:

    I had no idea this drug could be this bad. I’m very worried now after reading all these comments. I’m sick to my stomach. My doctor never told me about any of this.

    Posted on October 21, 2021 at 3:46 pm

  • Michelle says:

    Was subscribed Xenical by my cardiologist in Long Beach NY around 2006/2007, not for weight loss but as an alternative to cholesterol medication. I took it for about two years. Because I didn’t like the side effects. So I took myself off it. After a few months of taking it I noticed that there was a lot of oil in the toilet bowl after I pooped and it gave me very bad kidney infections and stomach cramps. I just thought this was a natural thing. But here we are today. I’m not a big drinker in fact I really don’t drink. Maybe one glass just for a toast. Ive developed kidney atrophy, lost my gallbladder, cyst on my kidneys, 4 precancerous liaison on my colon. No family history of any of these. My family always say was it those pills you took years ago. And after reading some of these comments I totally agree with them. I’m 5,7. My BMI is 30.1. 189lbs very active walk 10 miles a day, my family call me the ever ready battery because I’m always on the go. I try not to let stuff bring me down. But if pills like these are so safe why then are people coming down with so many issues. With their kidneys, with their liver. With their colon. Like it’s crazy. Company’s mask hidden dangers by changing or rebranding their brand. Why the FDA allows this is beyond me.

    Posted on February 12, 2023 at 7:54 am

Add Your Comments

  • Have Your Comments Reviewed by a Lawyer

    Provide contact information below and additional private comments if you want an attorney to contact you to review a potential case.

    The information below will not be published to this page.

  • NOTE: Providing information for review by an attorney does not form an attorney-client relationship.

  • This field is for validation purposes and should be left unchanged.