Rocephin injection could cause fatal reaction

Austin Kirk

By Austin Kirk
Posted September 13, 2007

ADD YOUR COMMENTS 5

An FDA Alert has been issued regarding updates to the label for Rocephin, an antibiotic injection.  A potentially fatal reaction could result for individuals of all ages if the injection is administered together with calcium containing products.

A prior warning issued in May 2007 indicated that combining Rocephin and calcium or calcium-containing products could cause a fatal reaction in the lungs and kidneys of new born babies.  Therefore, the FDA advised that the antibiotic injection should not be given to hyperbilirubinemic newborns, especially premature babies.

>>PRIOR POST 7/5/07: Rocephin injection linked to newborn deaths

While there have only been reports of deaths involving babies, the FDA indicates that the potential for this interaction exists in people of all ages.  Fatalities have been associated with the administration of calcium and Rocephin simultaneously, as well as at different times via different infusion lines.

Rocephin (ceftriaxone sodium) is an antibiotic injection manufactured by Roche Holding AG.  The new Rocephin warning indicates that the antibiotic injection should not be mixed with calcium or administered within 48 hours of a calcium containing product.

If you, a friend or loved one suffered a fatal reaction in the lungs or kidneys after receiving an antibiotic injection, the problems could have been caused by a combination of Rocephin and calcium.  To review your legal rights, request a free consultation.

5 Comments • Add Your Comments

  • Melvenia says:

    On 11/15/2017 my 17 year old daughter took a Rocephin injection in the clinic. And her doctor also prescribed 2 Azithromycin pills 500 mg. Now my daughter has stage 5 renal failure. She goes to diaylisis 3 times a week. Until she gets a kidney donor.

    Posted on January 29, 2018 at 12:42 pm

  • Suzanne says:

    OMG I am so very sorry to hear that. I will keep her in my prayers. I’m on rocephin now ever 12 hours threw my pickline sometimes I feel ill like they don’t deloot it enough. I am in hospital for 6 weeks and on this antibiotics.

    Posted on June 24, 2018 at 5:49 pm

  • Tina says:

    My mother died 10 mins after taking a shot of Rocephin at the urgent care. She sat in her car and went into cardiac arrest.

    Posted on January 30, 2025 at 6:50 pm

  • Tarka says:

    My brother was administered intravenously IV in the ER April 4, 2025 with 2000 mg of rocephin for urine tract affection 13 minutes into the medication blood pressure dropped went into a cardiac arrest they administered epinephrine at 2:16 PM unfortunately he did not survive. He passed April 5 at 1:23 PM from anaphylactic shock adverse reaction.

    Posted on April 14, 2025 at 1:28 pm

  • Coco says:

    My dad went in for neck pain and was given rocephin and clindamycin via IV. After a few minutes, he was gasping for air and died holding my daughter. I’m still in shock

    Posted on November 16, 2025 at 9:46 pm

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