Zelnorm alternatives following recent recall

Zelnorm was recently removed from the market after research linked the drug to an increased risk of heart attacks, strokes and other cardiovascular events.  Some individuals with constipation predominant IBS (irritable bowel syndrome) have been seeking Zelnorm alternatives to relieve their symptoms.

>>INFORMATION: Zelnorm Recall

In July 2002, the FDA approved Zelnorm (generic tegaserod maleate) for use in the United States.  The drug was intended to relieve symptoms of IBS with constipation by increasing movements of stools through the bowels.  However, it has never been very effective and when reports surfaced that Zelnorm side effects could cause serious and potentially fatal cardiovascular problems, the FDA requested that the drug be removed from the market on March 31, 2007.  It was determined that the risks outweighed the limited benefits of the drug.

Shortly after FDA approval, many experts and advocacy groups criticized the decision to approve Zelnorm since there was little proof that it relieved constipation any better than fiber supplements and other alternatives.  In Europe, Zelorm was rejected on two separate occasions.

Clinical studies have shown that Zelnorm provides no benefit for men with IBS-Constipation, and only 5% to 11% of women fared any better when taking the drug.  Therefore, many long-term sufferers have already been searching for an alternative to Zelnorm.

On various websites and internet forums, those with constipation predominant IBS have indicated that some of the following treatment alternatives have shown improvement of symptoms.  This information is not being provided as medical advice, but rather as a summary of information which some have indicated helped them.  None of the following should be tried without first consulting with your physician to discuss the benefits and risks associated with each Zelnorm alternative.

ALTERNATIVES FOR CONSTIPATION

  • Milk of magnesia - a fairly mild laxative which is gentle on the stomach
  • Miralax - a powerful laxative, which is referred to as an osmotic laxative since it draws water into the bowel
  • Amitiza - medication which is designed for chronic constipation
  • Kristalose - a prescription laxative which can treat

NATURAL ALTERNATIVES

  • Magnesium Supplements - magnesium oxide and magnesium citrate
  • Acacia - organic soluble fiber which can help relieve constipation
  • Fennel - fennel seed tea can be beneficial for bloating
  • Peppermint - enteric coated peppermint oil has been reported to relieve and prevent abdominal pain, bloating and discomfort
  • Probotic foods - foods which could help calm IBS include sauerkraut, yogurt, cheese, buttermilk, kefir, soy sauce, tofu and unpasteurized beer
  • Hypnotherapy - gut-directed hypnotherapy can address the underlying pathology of bowel dysfunctions and improve symptoms

ZELNORM LAWYERS

The Zelnorm lawyers at Saiontz, Kirk & Miles, P.A. represent individuals who have suffered a heart attack, stroke or ischemic colitis after taking the IBS drug.  The FDA has indicated that users looking for a Zelnorm alternative should speak with their healthcare providers.  New treatments should always be reviewed with your physician to discuss potential benefits and side effects.

If you, a friend or family member wish to speak with an attorney about your legal alternatives and Zelnorm lawsuits which are being pursued, request a free consultation and claim evaluation.

>>REQUEST A ZELNORM LAWSUIT EVALUATION<<

4 Responses to:
“Zelnorm alternatives following recent recall”

  1. Jean Burke Says:

    I used Zelnorm for 1.5 years with miraculous results in treatment for a megacolon = chronic intractable constipation. My GI physician proposed treatment with Zelnorm saying that it would ONLY work IF the constipation arose from a problem with the colonic nervous system, i.e. if the nervous system in the colon was not transmitting messages effectively. He said it was only effective in 1 of 4 patients. It was a wonder drug for me. Nothing else worked - not fiber, not a vegetarian/vegan diet, not naturopathy or homeopathics, not colonic irrigation, not even laxatives. I was ready to say that surgical removal of the colon was the only way to go when my physician told me about the “new drug” Zelnorm, and it made my life liveable.

    You are misrepresenting the situation when you say that Zelnorm was “never very effective.” The target population was always understood to be small. In addition, my understanding is that only patients with risk factors for CV problems were adversely affected by this drug, which means that patients WITHOUT risk factors could probably take this drug safely and with GREAT BENEFIT.

    I am a Paralegal working in Canada in the field of personal injury. I have high regard for lawyers as guardians of the rule of law and fair treatment of persons injured by negligence, and through no fault of their own. You are giving lawyers a bad name by misrepresenting the facts about use of Zelnorm, as you have done on this web page. Who are you seeking to beneft?

  2. sheila gay Says:

    I have been on zelnorm, for a period of 8 or 10 years. I now have IBS from takeing zelnorm. I have adominal cramping, from eating certain foods.I stay bloated all the time. I have contipation problems. which zelnorm did not help.I uaually go to the bathroom about once every 2 weeks. I now have crohns disease.And colitis of the bowels. I also experince chest pains. I have been to my DR. for this problem, and he told me to flush the zelnorm down the toilet. I never had any of these problems, until I started taking Zelnorm.

  3. Austin Kirk Says:

    Ms. Burke, Thank you for sharing your experiences. Certainly you are not alone as an IBS sufferer who found Zelnorm effective in treating your symptoms. However, the clinical studies have demonstrated that it is effective for a very small number of users (approximately 5-11% of female patients). In addition, wide promotion of this medication by the manufacturer has resulted in many users receiving the drug off-label, even though it is only intended for IBS with constipation.

    The FDA has recognized that there is a population for whom Zelnorm may be an acceptable treatment alternative, and they have indicated that it is possible the drug could be reintroduced in the future for a much more limited and controlled population to reduce the risk of heart attack, stroke and death associated with the drug. At this time they have found the risk of Zelnorm side effects outweighs the very limited benefits the drug provided, which is whyit has been removed from the market.

    Our office has been contacted by many Zelnorm users who did not have the same experiences as you, many of whom suffered heart attacks, strokes and ischemic colitis which could have been avoided if the manufacturer had warned of the danger.

  4. Tanya Francis Says:

    I have to agree with Ms Burke. I have severe IBS with constipation effecting my entire digestive track. I went for months with other medications where I was throwing up my bowel and had pain worse then when I had 2 kidney stones. Zelnorm was the only thing that worked for me and allowed me to start being able to function daily. I understand that some people have had problems with it but that happens with any drug. I can’t understand why it is not made available for those of us that have had no problems after a year and half of taking it as long as we understand the possible risks. For myself the risk is better then what I have had to go through on a day to day basis since Zelnorm was taken off the markey last year.

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