Actos and Avandia heart failure risk confirmed

Harvey Kirk

By Harvey Kirk
Posted October 2, 2007

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A new study confirms that the diabetes drugs Actos and Avandia increase the risk of heart failure.  Both drugs previously received a “black box” warning about congestive heart failure in June, and they have been the subject of several studies since a report in published in May found that users of Avandia face a 43% increase in the  risk of heart attacks and a 64% increase in the risk of heart related deaths.

>>INFORMATION: Avandia Heart Problems

Avandia, made by GlaxoSmithKline, and Actos, manufactured by Takeda Pharmaceutical Co. Ltd, are bother part of the same class of medications.  They are prescribed for treatment of type 2 diabetes, but many experts and physicians are questioning whether the drugs provide sufficient benefits to justify the risk of heart problems.

The new study, published in the September 29 issue of The Lancet, does not reach any conclusions about the heart attack risk which has been the focus of most of the concerns.  However, researchers did confirm that users of Actos and Avandia could face up to a 72% increase in the risk of congestive heart failure.

Heart failure is a chronic condition where the heart fails to pump blood efficiently.  Those with milder cases may experience fatigue or a need to limit physical activities.  However, those with severe cases of heart failure could have fluid build up in the lungs which can be fatal.

Researchers reviewed data from seven clinical trials involving more than 20,000 patients.  The  data included  those with type 2 diabetes without cardiovascular disease, those with type 2 diabetes and cardiovascular disease, those with type 2 diabetes and a history of congestive heart failure, and those with “pre-diabetes”.

AVANDIA HEART FAILURE LAWSUITS

The lawyers at Saiontz & Kirk, P.A. are reviewing potential Avandia lawsuits for users of the diabetes drug who suffered a heart attack, stroke, congestive heart failure or death.  If you, a friend or family member suspect that heart failure may have been caused by Avandia, request a free claim evaluation.

4 Comments • Add Your Comments

  • BRUCE says:

    I have been an actos patient for the last 3 or 4 years, increasing from 5mg. to 30mg. and was told to stop taking this drug on the 2nd or 3rd of September.
    My question is, I suffered Cardiac Arrest at Home on May 26, 2009, I was shocked back to life and had a defibulator installed on May 28, 2009.
    My heart is currently in “A” Fib, and am being treated for this, which will include shocking the heart if I do not go back into normal rythym.
    Should I be concerned that this may have all been caused by the ACTOS medication I have been taking.

    Posted on September 7, 2010 at 1:33 pm

  • carolina says:

    i recently was prescribed actos 15mg and januvia 50mg to help lower blood sugar and after reading statements on januvia and actos should i take it or request different meds.

    Posted on June 3, 2011 at 6:32 pm

  • carolina says:

    i recently was prescribed actos 15mg and januvia 59mg to help lower my blood sugar. After reading the comments on actos and januvia should i take these meds or request other meidication

    Posted on June 3, 2011 at 6:38 pm

  • James says:

    Actos I am sure caused my AFIB, and serious health damage. But I can get no legal help at all.

    Posted on September 19, 2014 at 3:37 pm

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