Zocor Rhabdomyolysis Side Effects at 80mg Dose
As a result of an increased risk of muscle injury, myopathy and rhabdomyolysis from Zocor side effects, the FDA is calling for severe limits on the use of the cholesterol drug simvastatin at its highest dose. The product liability lawyers at Saiontz & Kirk, P.A. are reviewing potential Zocor lawsuits for individuals who have experienced severe muscle problems, as it appears that the manufacturer should have issued these warnings some time ago.
On June 8, the FDA indicated that new warnings will be added to the label for choleterol-lowering medications containing simvastating, indicating that 80 milligram dose has been associated with an increased risk of muscle injury or myopathy, especially during the first year of use. The medication is most commonly known as Zocor, but is also available as generic simvastatin. It is also used in combination with other drugs in the medications Vytorin and Simcor.
Doctors have been warned not to start new patients on 80 mg Zocor (simvastatin) prescriptions and to only use this highest dose among patients who have been taking 80mg Zocor for at least 12 months and have not experienced any muscle problems. The agency also added new contraindications and dose limitations when simvastatin is taken with certain other medications.
Zocor rhabdomyolysis side effects may cause nearly 5 out of every 100,000 people who regularly take Zocor 80mg dose to be hospitalized. Rhabdomyolysis from Zocor is a rare but serious and potentially life-threatening injury, which causes muscle tissue to break down and can lead to kidney damage or kidney failure.
Symptoms of Zocor rhabdomyolysis or muscle problems may include:
- Muscle Cramps
Until 2005, when generic versions became available, Zocor (simvastatin) was a top selling drug for Merck and remains popular today. Zocor or other drugs containing simvastatin, including Vytorin and Simcor, were used by 2.1 million Americans last year.
Zocor is a member of a family of cholesterol-lowering drugs known as statins. While all statins carry some risk of rhabdomyolysis and myopathy, the risk appears to be unacceptably high with 80 mg doses of simvastatin. That risk is increased even further when combined with certain other drugs and in people who are genetically predisposed to Zocor rhabdomyolysis.
The FDA released these new recommendations and warnings after reviewing clinical trial data and other information which has been available to the manufacturers for some time.
ZOCOR LAWSUIT EVALUATIONS
Individuals who have suffered Zocor muscle problems or rhabdomyolysis after using 80 mg simvastatin may be entitled to compensation through a Zocor lawsuit as a result of the manufacturer’s failure to fully research the side effects of simvastatin at high doses or adequately warn about the risk of Zocor problems.
The Zocor lawyers at Saiontz & Kirk, P.A. are providing free consultations and claim evaluations to help individuals determine whether they may have a claim. To review a potential Zocor rhabdomyolysis lawsuit for yourself, a friend or family member, request a free consultation and claim evaluation.