Lawyers Reviewing Proton Pump Inhibitor (PPI) Lawsuits

Proton Pump Inhibitors (PPI) are a class of drugs used for treatment of acid reflux, heartburn, ulcers and other gastroinstestinal problems. Members of this class include popular medications like Nexium, Prilosec, Prevacid, Protonix, AcipHex, Dexilant, Vimovo, Zegerid and others.

These heartburn drugs are promoted as safe and effective, leading many to continue using the medications for years. However, it appears that drug manufacturers may have failed to adequately warn about a number of serious and potentially life-threatening side effects of proton pump inhibitors (PPI).

The lawyers at Saiontz & Kirk, P.A. are reviewing potential proton pump inhibitor (PPI) lawsuits for individuals nationwide who have experienced kidney problems, including:

  • Acute Kidney Injury
  • Acute Interstitial Nephritis
  • Chronic Kidney Disease
  • Renal or Kidney Failure
  • Dialysis Treatment
  • Kidney Transplant Surgery

As a result of the drug makers’ failure to warn about the kidney injury risks with proton pump inhibitors, financial compensation may be available. To review a case for yourself or a loved one, request a free consultation and claim evaluation.

Proton Pump Inhibitor Kidney Problems

Proton Pump Inhibitors (PPI) work by reducing the amount of stomach acid produced, reducing symptoms of heartburn and pain caused if stomach juice backs up into the esophagus. This also allows the esophagus to heal.

Medications like Nexium, Prilosec, Protonix and others have been used by millions of Americans, generating billions in revenue each year for the drug makers. However, concerns have existed for years that the PPI drugs are widely overused, often without re-evaluation to determine the need for continued treatment or any attempts to reduce use.

Due to the assumption that proton pump inhibitors are safe, many individuals have continued to use the medications for years. However, it appears that important safety information may have been withheld from consumers and the medical community.

Many individuals may have been able to avoid severe kidney problems from proton pump inhibitors (PPI) if stronger warnings had been provided about the potential risks associated with long-term PPI use.

Several studies have highlighted a link between proton pump inhibitors and kidney injury, which has not been adequately disclosed on the warning labels for Nexium, Prilec, Protonix and other PPIs. This has prevented individuals and doctors from making an informed decision about whether the continued use of proton pump inhibitors are justified.

▸ Acute Interstitial Nephritis

Evidence suggests that proton pump inhibitors increase the risk of acute interstitial nephritis, which involves inflammation of the kidneys that may lead to chronic and long-term injury if the drug is not discontinued.

In late 2014, the FDA announced new proton pump inhibitor warnings would be added to the medications, including information for the first time that the drugs may cause acute interstitial nephritis, which may have caused many individuals suffering from this kidney complication to continue using the drugs since doctors were previously unaware of the connection.

Acute interstitial nephritis from proton pump inhibitors may cause symptoms like nausea, vomiting, fatigue and sudden weight loss. However, in severe cases this may lead to chronic kidney damage and kidney failure.

▸ Acute Kidney Injury

In April 2015, a study published in the medical journal CMAJ Open highlighted the risk of acute kidney injury with proton pump inhibitors.

Researchers from the Institute for Clinical Evaluative Sciences and St. Michael’s Hospital in Toronto examined data on 300,000 older individuals and found that those who started PPI drugs had a 2.5 fold increased risk of acute kidney injury, as well as 3 times higher risk of acute interstitial nephritis when compared to individuals who did not use the drugs.

Acute kidney injury involves the abrupt loss of kidney function, which may occur after taking a PPI drug. While many individuals regain normal kidney function, approximately 10% of patients with acute kidney failure may be permanently impacted, causing end-stage kidney failure and other complications.

▸ Chronic Kidney Disease

In January 2016, concerns about the PPI kidney risks were further increased with the publication of a study in the medical journal JAMA Internal Medicine, which found that the heartburn drugs may also increase the risk of chronic kidney disease (CKD) by 50%.

Researchers examined data on more than 10,000 participants over a period of more than 10 years, finding that compared with those who did not use the drugs, PPI treatments were associated with a higher incidence of chronic kidney disease. These findings have led researchers to call for further studies to evaluate whether limiting PPI use may mitigate the risk.

Experts have pointed out that the risk of chronic kidney disease from proton pump inhibitors likely stems from recurrent acute kidney injury or interstitial nephritis.

Chronic kidney disease from proton pump inhibitors may cause wastes to build up to high levels in the blood, which may eventually lead to kidney failure, the need for life-long dialysis treatments or a kidney transplant surgery.

Proton Pump Inhibitor Lawyers

Many individuals have continued to take proton pump inhibitors long after there is any clearly justified medical reason, which was largely caused by the drug makers’ failure to warn about the risk of severe injuries associated with long-term use of Nexium, Prilosec, Protonix, Prevacid or other PPIs.

Among individuals with less severe symptoms, some experts have suggested that the proton pump inhibitor risks may outweigh the benefits provided.

As a result of the failure to warn about the kidney damage risk, which may lead to the need for dialysis treatment, kidney failure and a potential kidney transplant, financial compensation may be available through a Nexium lawsuit, Prilosec lawsuit or other proton pump inhibitor (PPI) kidney injury lawsuit.

The lawyers at Saiontz & Kirk, P.A. are pursuing all proton pump inhibitor (PPI) cases under a contingency fee agreement, which means that there are never any out-of-pocket costs to hire our law firm and we only receive an attorney fee or reimbursed expenses if we are successful obtaining a recovery or settlement in your case.

Free consultations and claim evaluations are provided to help individuals and families throughout the U.S. determine what legal options may be available for those who have suffered PPI kidney damage.