Heartburn Medication Kidney Failure and Chronic Kidney Disease Risk
October 2023 Update: Following an October 2023 PPI heartburn drug lawsuit settlement, Saiontz & Kirk, P.A. is no longer reviewing new potential cases. The information on this page is for informational purposes only.
It is becoming increasingly clear that the makers of Nexium, Prilosec, Dexilant, Protonix, Prevacid, AcipHex and other proton pump inhibitors (PPI) have failed to adequately research the side effects of their medications or warn about the potential kidney risks.
In a study published by the Journal of the American Society of Nephrology on April 14, researchers from St. Louis examined databases from the Department of Veteran Affairs to evaluate kidney outcomes among more than 170,000 users of PPI drugs.
The incidents of chronic kidney disease and end stage kidney failure among users of Nexium, Prilosec and other PPI medications was compared to the risk among individuals who received a different type of heartburn medication, known as H2 blockers, which include Zantac, Pepcid, Tagamet and others.
Among the findings, users of Nexium, Prilosec and other PPI-based heartburn drugs had a:
- 28% increased risk of Chronic Kidney Disease (CKD);
- 96% increased chance of end-stage renal failure, or kidney failure, within five years of starting to use the drugs;
- Greater kidney damage risk the longer Nexium or other heartburn drugs are used;
- 15% of PPI users will develop chronic kidney disease within five years.
This research adds to the findings of two prior studies on the link between Nexium and kidney problems, which were published by the medical journal CMAJ Open in April 2015 and JAMA Internal Medicine January 2016.
Heartburn Drug Lawsuits
While most consumers are just starting to learn about the kidney risks from Nexium, Prilosec and other heartburn drugs, manufacturers knew or should have known about the potential side effects for years.
As a result of the apparent decision to place their desire for profits before consumer safety, financial compensation was made available in October 2023 for certain individuals who suffered side effects, including:
- Acute Interstitial Nephritis
- Acute Kidney Injury
- Chronic Kidney Disease
- End Stage Renal Disease or Kidney Failure
- Dialysis Treatment
- Kidney Transplant
- Wrongful Death
New proton pump inhibitor (PPI) cases are no longer being investigated by Saiontz & Kirk, P.A. The content on this page is for informational purposes only.