Dexilant Lawyers for Kidney Injury and Stomach Cancer Lawsuits

The product liability lawyers at Saiontz & Kirk, P.A. are reviewing potential Dexilant lawsuits for individuals nationwide who have been diagnosed with stomach cancer or developed serious kidney problems following use of this popular acid reflux and heartburn drug, which is part of a class of medications known as proton pump inhibitors (PPI).

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Saiontz & Kirk, PA, Attorneys & Lawyers, Baltimore, MD

Dexilant (dexlansoprazole) was introduced in January 2009, originally sold under the brand name Kapidex. It was a new addition to a blockbuster class of acid reflux drugs, which includes Nexium, Prilosec and other medications that are used by millions of individuals.

While the medications have been promoted as safe and effective, recent studies have found that side effects of Dexilant and other proton pump inhibitors (PPI) may increase the risk of serious and potentially life-threatening injuries, which were not adequately disclosed by the drug maker, including:

  • Stomach Cancer or Gastic Cancer
  • Acute Kidney Injury
  • Acute Interstitial Nephritis
  • Chronic Kidney Disease
  • Kidney Failure

If information had been provided to consumers and the medical community about the potential Dexilant side effects, many people may have limited their use of this drug or selected a different treatment alternative for their acid reflux symptoms.

Contact our Dexilant lawyers to review whether your or a loved one may be entitled to financial compensation. Request a free consultation and claim evaluation.

Dexilant Side Effects

Dexilant is manufactured and sold by Takeda Pharmaceuticals. It was originally introduced under the brand name Kapidex, but the name was changed about a year later due to confusion with other drugs, such as Casodex and Kadian.

Proton pump inhibitors like Dexilant are commonly used to treat symptoms of gastroesophageal reflux disease (GERD), as well as heartburn, stomach ulcers and inflammation of the esophagus. Nexium, Prilosec and other PPIs have generated billions in sales each year, and Dexilant is one of the last members of this class that does not face generic competition.

When Dexilant was introduced, the drug was almost immediately under fire by consumer groups like Public Citizen, which listed it on its “worst pills” list, indicating that it had no advantages over other PPIs already on the market. The group pointed out that the sole purpose of introducing the medication was to allow Takeda Pharmaceuticals to charge three times the cost of generic PPIs already on the market.

Although it appears that the drug maker knew or should have known about the Dexilant kidney problems and potential risk of stomach cancer, Takeda Pharmaceuticals placed its desire for profits before consumer safety by aggressively marketing the drug while withholding warnings from consumers and the medical community.

▸ Dexilant Stomach Cancer Cases

Gastric cancer or stomach cancer can develop in the lining of the stomach following long-term use of Dexilant or another proton pump inhibitor. In December 2017, a study published by Hong Kong researchers found that the medications may more than double the risk, while other types of heartburn drugs were not linked to the same side effects.

Following publication of a second study in The British Medical Journal, a number of experts have raised questions about why the Dexilant cancer risks were not studies before this newer PPI was ever introduced. Researchers indicated that users of any PPI drug may face up to a three times higher risk of stomach cancer following long-term use, yet warnings were not provided to users or the medical community.

The lawyers at Saiontz & Kirk, P.A. are evaluating the potential for Dexilant stomach cancer lawsuits, and provide free consultations and claim evaluations to help individuals and families determine whether they may be entitled to financial compensation.

▸ Dexilant Interstitial Nephritis Warnings

Reports of acute interstitial nephritis among users of Dexilant and other proton pump inhibitors were the first signs of problems with Dexilant and other PPI drugs.

In December 2014, the FDA required new warning information about a form of Dexilant kidney problems, known as acute interstitial nephritis, which involves a sudden inflammation of the kidneys that can lead to more severe problems.

The new warning information states:

Acute interstitial nephritis has been observed in patients taking PPIs including [Dexilant]. Acute interstitial nephritis may occur at any point during PPI therapy and is generally attributed to idiopathic hypersensitivy reaction. Discontinue Dexilant if acute interstial nephritis develops

According to allegations that will be raised in Dexilant injury lawsuits, these warnings should have been provided much earlier and also do not go far enough, as there is no mention of the word “kidney” in either the prescribing information or medication guide provided by the drug maker.

Consumers and the medical community should be informed that side effects of Dexilant may increase the risk of serious and life-threatening kidney problems, including acute kidney injury, chronic kidney disease, kidney failure and other problems.

▸ Dexilant Acute Kidney Injury Risk

In a study published by the medical journal CMAJ Open in April 2015, researchers found that use of proton pump inhibitors like Dexilant may cause some users to face a 2.5 fold increased risk of acute kidney injury (AIN), as well as a three times higher risk of acute interstitial nephritis (AIN) when compared to individuals who do not use a heartburn drug.

Researchers highlighted the importance of doctors understanding the risk of acute interstitial nephritis and kidney injury with drugs like Dexilant, indicating that patients should be monitored and indiscriminate use of the drugs should be discouraged. However, no additional Dexilant kidney warnings have been provided by Takeda Pharmaceuticals for users or the medical community.

In severe cases, a Dexilant acute kidney injury may become chronic, leading to kidney disease, end-stage renal failure, the need for life-long dialysis treatment or a kidney transplant.

▸ Dexilant Kidney Disease

In January 2016, another study published in the medical journal JAMA Internal Medicine highlighted the link between Dexilant and kidney problems, finding that proton pump inhibitors (PPI) may increase the chances of individuals developing chronic kidney disease (CDK) by 50%.

Researchers called for further research on the link into the chronic kidney disease risk with Dexilant and other PPIs. Lawsuits over Dexilant allege that information provided by the drug maker should more clearly indicated that Dexilant can cause sudden loss of kidney function, potentially resulting in symptoms like:

  • Weakness or Fatigue
  • Shortness of Breath
  • Abnormal Heart Rhythms
  • Pain the Flanks

Recurrent kidney injury or more severe instances may be the underlying cause of chronic kidney disease from Dexilant, and many individuals may have avoided this serious complication by discontinuing the drug or pursuing a different treatment alternative.

It appears that Takeda placed their desire for profits ahead of consumer safety by failing to provide adequate information and warnings about these potential Dexilant kidney risks.

Dexilant Class Action Lawyers

The lawyers at Saiontz & Kirk, P.A. are reviewing potential Dexilant class action lawsuits and individual claims for those who have suffered a kidney injury or stomach cancer. Similar claims are being through Nexium lawsuits, Prilosec lawsuits, Prevacid lawsuits, Protonix lawsuits and cases for users of other PPI medications.

All claims are reviewed by our lawyers on a contingency fee basis, which means that there are no out-of-pocket costs to hire our law firm and we only receive an attorney fee or reimbursed expenses if we are successful obtaining a Dexilant settlement or recovery or a kidney injury suffered by you or a loved one.